ArticleResearch square2025
Visualizing cortical laminar architecture in the living human brain using next-generation ultra-high-gradient diffusion MRI.
Susie Huang, Hansol Lee, Yixin Ma, Kwok-Shing Chan, Eva Krijnen, Laleh Eskandarian, Aneri Bhatt, Julianna Gerold, Mirsad Mahmutovic, Oula Puonti and 7 more
Abstract readPreprint
In one paragraphArticle in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
17 authors.
Yixin Ma
Kwok-Shing Chan
Eva Krijnen
Laleh Eskandarian
Mirsad Mahmutovic
Oula Puonti
Xiangrui Zeng
Lucas Jacob Deden Binder
Boris KeilMittelhessen University of Applied Science.
Gabriel Ramos-Llordén
Eric Klawiter
Funding
CONNECTOME 2.0: DEVELOPING THE NEXT GENERATION HUMAN MRI SCANNER FOR BRIDGING STUDIES OF THE MICRO-, MESO- AND MACRO-CONNECTOMEU01EB026996 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BASSER, PETER J., HUANG, SUSIE YI · 2018 to 2022
$14.2MTraining and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2020 to 2026
$10.9MProject 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8MConnectome 2.0: A BRAIN Technology Integration and Dissemination Resource for Ultra-High Gradient Magnetic Resonance Imaging of Human Brain Circuits Across ScalesU24NS137077 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2024 to 2026
$4.0MToward a Validated in Vivo Imaging Marker of Axonal Damage Predictive of Progressive Disability in Multiple SclerosisR01NS118187 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HUANG, SUSIE YI · 2021 to 2025
$2.8MRevealing tissue microstructure in the brain gray matter in Alzheimer's disease using in vivo high-gradient diffusion MRIDP5OD031854 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HONG HSI · 2021 to 2025
$2.1MNIBIB NIH HHS P41 EB015896NIBIB NIH HHS P41 EB030006NIBIB NIH HHS U01 EB026996NIH HHS DP5 OD031854NINDS NIH HHS R01 NS118187NINDS NIH HHS U24 NS137077
6 · The paper itselfAbstract
Characterizing cortical laminar microstructure is essential for understanding human brain function. Leveraging the next-generation Connectome MRI scanner (maximum gradient strength = 500mT/m, slew rate = 600T/m/s), we characterized
Indexed as
Connectome 2.0Cortical microstructureCytoarchitectureDiffusion MRIHigh-performance gradientLaminar organizationMyeloarchitectureSANDI Model
Identifiers
PMID40585214
PMCPMC12204490
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390