Evidence map›Paper›PMID 40585120›Full record

ArticlemedRxiv : the preprint server for health sciences2025

SmokeBERT: A BERT-based Model for Quantitative Smoking History Extraction from Clinical Narratives to Improve Lung Cancer Screening.

Yiming Xue, Yunzheng Zhu, Luoting Zhuang, YongKyung Oh, Ricky Taira, Denise R Aberle, Ashley E Prosper, William Hsu, Yannan Lin

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Yiming XueDepartment of Statistics & Data Science, University of California, Los Angeles, CA, USA.
Yunzheng ZhuMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Luoting ZhuangMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
YongKyung OhMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Ricky TairaMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Denise R AberleMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Ashley E ProsperMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
William HsuMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Yannan LinMedical & Imaging Informatics, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Funding

EFIRM Liquid Biopsy Research Laboratory: Early Lung Cancer AssessmentU01CA233370 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ABERLE, DENISE R., HSU, WILLIAM · 2018 to 2025
$8.0M
The Boston University - UCLA Lung Cancer Biomarker Characterization CenterU2CCA271898 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Jennifer Ellen Beane, Steven M. Dubinett · 2022 to 2026
$5.5M
NCI NIH HHS U01 CA233370NCI NIH HHS U2C CA271898
6 · The paper itself

Abstract

Tobacco use is a critical risk factor for diseases such as cancer and cardiovascular disorders. While electronic health records can capture categorical smoking statuses accurately, granular quantitative details, such as pack years and years since quitting, are often embedded in clinical narratives. This information is crucial for assessing disease risk and determining eligibility for lung cancer screening (LCS). Existing natural language processing (NLP) tools excelled at identifying smoking statuses but struggled with extracting detailed quantitative data. To address this, we developed SmokeBERT, a fine-tuned BERT-based model optimized for extracting detailed smoking histories. Evaluations against a state-of-the-art rule-based NLP model demonstrated its superior performance on F1 scores (0.97 vs. 0.88 on the hold-out test set) and identification of LCS-eligible patients (e.g., 98% vs. 60% for ≥20 pack years). Future work includes creating a multilingual, language-agnostic version of SmokeBERT by incorporating datasets in multiple languages, exploring ensemble methods, and testing on larger datasets.

Identifiers

PMID40585120
PMCPMC12204286

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.