Evidence map›Paper›PMID 40585101›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Clinical and epidemiological characteristics among probable and confirmed patients with mpox in Sierra Leone reported from January to May 2025.

Jia B Kangbai, Emmanuel Saidu, Ibrahim K Foday, Emmanuel S Kamanda, Michaella Jaba, Allan Campbell, Alie Brima Tia, Christopher M Ruis, Lorenzo Subissi, Megan Halbrook and 9 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jia B KangbaiDepartment of Public Health, Njala University, Bo, Sierra Leone.
Emmanuel SaiduDepartment of Biological Sciences, Njala University, Bo, Sierra Leone.
Ibrahim K FodayDepartment of Biological Sciences, Njala University, Bo, Sierra Leone.
Emmanuel S KamandaDepartment of Biological Sciences, Njala University, Bo, Sierra Leone.
Michaella JabaDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Allan CampbellCentral Public Health Research Laboratory, Lakka, Sierra Leone.
Alie Brima TiaSierra Leone-China Friendship Biological Safety Laboratory, Freetown, Sierra Leone.
Christopher M RuisWorld Health Organization, Geneva, Switzerland.
Lorenzo SubissiWorld Health Organization, Geneva, Switzerland.
Megan HalbrookDepartment of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California, USA.
Sydney MerrittDepartment of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California, USA.ORCID 0000-0002-4039-605X
Nicole A HoffDepartment of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California, USA.
Eddy Kinganda-LusamakiService de Microbiologie, Département de Biologie Médicale, Cliniques Universitaires de Kinshasa, Université de Kinshasa.
Laurens LiesenborghsDepartment of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0001-5616-8548
Isaac I BogochDivisions of Infectious Diseases and General Internal Medicine.ORCID 0000-0003-1590-6748
Souradet Y ShawDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Placide Mbala-KingebeniService de Microbiologie, Département de Biologie Médicale, Cliniques Universitaires de Kinshasa, Université de Kinshasa.
Anne W RimoinDepartment of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, California, USA.ORCID 0000-0002-0662-9067
Jason KindrachukDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-3305-7084

Funding

Emerging Infectious Diseases Research Center - East and Central AfricaU01AI151799 · NIAID · WASHINGTON STATE UNIVERSITY · PI M KARIUKI NJENGA · 2020 to 2026
$10.4M
Training and Research on Arboviruses and Zoonoses In Nigeria and Sierra Leone (TRAIN)D43TW012246 · FIC · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Nikos Vasilakis, Scott C Weaver · 2022 to 2026
$1.2M
FIC NIH HHS D43 TW012246NIAID NIH HHS U01 AI151799
6 · The paper itself

Abstract

We analyzed available mpox cases reports in Sierra Leone from January to June 2025 following a historic increase in mpox cases across multiple urban and rural regions in the country. Here, we assessed demographic and clinical data from 187 case reports. Mpox case reports in this study were primarily from Bo (86/187; 46.0%) and Freetown (48/124; 25.7%). Most case reports were from male patients (101/187; 54.0%) as compared to females (86/187; 46.0%), with an overall median age of 26 years (IQR 22-34). The median age was higher among males (30 years; IQR 25-39) then females (24 years; IQR 21-27). Rash, fever, headache, lesions, and generalized pain were reported for all patients, where data was reported. Lymphadenopathy, muscle pain, sore throat, and cough were reported less commonly. Age- and sex-specific interventions, as well as community engagement that includes historically stigmatized groups are critical for mpox containment and mitigation measures in Sierra Leone.

Indexed as

clinical characteristicsdemographicsepidemiologympoxmpox virusoutbreakSierra Leone

Identifiers

PMID40585101
PMCPMC12204408

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.