ArticlemedRxiv : the preprint server for health sciences2025
Brain-heart-eye axis revealed by multi-organ imaging, genetics and proteomics.
MULTI consortium, Aleix Boquet-Pujadas, Filippos Anagnostakis, Michael R Duggan, Cassandra M Joynes, Arthur W Toga, Zhijian Yang, Keenan A Walker, Christos Davatzikos, Junhao Wen
Abstract readPreprint
In one paragraphArticle in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
10 authors.
MULTI consortium
Aleix Boquet-PujadasLaboratory of AI and Biomedical Science (LABS), Columbia University, New York, NY, USA.
Filippos AnagnostakisLaboratory of AI and Biomedical Science (LABS), Columbia University, New York, NY, USA.
Michael R DugganLaboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Cassandra M JoynesLaboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Arthur W TogaLaboratory of Neuro Imaging (LONI), Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-7902-3755 Zhijian YangGE Healthcare, Bellevue, WA, USA.
Keenan A WalkerLaboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.ORCID 0000-0002-5989-9853 Christos DavatzikosArtificial Intelligence in Biomedical Imaging Laboratory (AIBIL), Center for AI and Data Science for Integrated Diagnostics (AID), Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
Funding
USCADRC Diversity Supplement PachicanoP30AG066530 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HELENA Chang CHUI · 2020 to 2026
$27.8MMachine Learning and Large-scale Imaging analytics for dimensional representations of brain trajectories in aging and preclinical Alzheimer's Disease: The brain aging chart and the iSTAGING consortiumRF1AG054409 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2023
$6.3MNIA NIH HHS P30 AG066530NIA NIH HHS RF1 AG054409
6 · The paper itselfAbstract
Multi-organ research investigates interconnections among multiple human organ systems, enhancing our understanding of human aging and disease mechanisms. Here, we used multi-organ imaging (
Identifiers
PMID40585072
PMCPMC12204406
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