Leveraging femtosecond laser machining for the fabrication of tubular-based Organ-on-Chip systems: modeling cancer metastasis from invasion to intravasation.

Mohammad Jouybar, Oscar Stassen, Hamed Moradi, Pan Zuo, Jaap M J den Toonder

Abstract read

In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad JouybarMicrosystems, Department of Mechanical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

Oscar StassenMicrosystems, Department of Mechanical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

Hamed MoradiDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

Pan ZuoMicrosystems, Department of Mechanical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

Jaap M J den ToonderMicrosystems, Department of Mechanical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ-on-Chip (OoC) models often include microchannel-based vessels and ducts with rectangular cross-sections, and therefore these lack the geometry and morphology found in tubular structures in vivo. Channels with round cross-sections can better mimic the physiology and cellular behavior of tubular structures, such as (micro)vessels and breast ducts, by providing a more

Indexed as

Cancer intravasationCancer invasionCancer-on-ChipMetastasisMicrofluidicsOrgan-on-ChipTubular channelTumor microenvironment

Identifiers

PMID40585039

DOI10.1016/j.mtbio.2025.101926

PMCPMC12205662

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.