Evidence map›Paper›PMID 40585027›Full record

ArticleMaterials today. Bio2025

Virtual testing methodology to predict the mechanical behavior of collagen hydrogels from nanoarchitecture.

Elías Núñez-Ortega, Pablo Blázquez-Carmona, Raquel Ruiz-Mateos, José E Martín-Alfonso, José A Sanz-Herrera, Esther Reina-Romo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elías Núñez-OrtegaEscuela Técnica Superior de Ingeniería, Universidad de Sevilla, Avenida Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Pablo Blázquez-CarmonaDepartamento de Ingeniería Mecánica y Diseño Industrial, Escuela Superior de Ingeniería, Universidad de Cádiz, Avenida Universidad de Cádiz 10, 11519, Puerto Real, Cádiz, Spain.
Raquel Ruiz-MateosEscuela Técnica Superior de Ingeniería, Universidad de Sevilla, Avenida Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
José E Martín-AlfonsoCentro de Investigación en Tecnología de Productos y Procesos Químicos (ProTecS), Departamento de Ingeniería Química y Ciencia de los Materiales, Escuela Técnica Superior de Ingeniería, Universidad de Huelva, Avenida de las Fuerzas Armadas s/n, 21007, Huelva, Spain.
José A Sanz-HerreraEscuela Técnica Superior de Ingeniería, Universidad de Sevilla, Avenida Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Esther Reina-RomoEscuela Técnica Superior de Ingeniería, Universidad de Sevilla, Avenida Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collagen-based hydrogels are three-dimensional, cross-linked structures capable of mimicking the extracellular fibered matrix of biological tissues, making them particularly well-suited for biomedical applications. These hydrogels typically exhibit highly non-linear mechanical behavior, which strongly depends on their internal nanostructural characteristics - an interconnection that remains poorly understood. The aim of this work is to combine high resolution imaging with a multiscale

Indexed as

Collagen-based hydrogelsFiber structuresFIB-SEMHomogenizationIn silico modelMechanobiologyRheology

Identifiers

PMID40585027
PMCPMC12205682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.