Evidence map›Paper›PMID 40585006›Full record

ArticleTopics in spinal cord injury rehabilitation2025

Different Circulating Endothelial Microvesicle Subtype Signature in Subacute and Chronic Spinal Cord Injury.

Andrew J Park, Hannah K Fandl, Vinicius P Garcia, Auburn R Berry, Kendra N Wegerson, Emily I Ostrander, Hannah L Cardenas, Noah M DeSouza, Jared J Greiner, Brian Stauffer and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Topics in spinal cord injury rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrew J ParkRocky Mountain Regional Spinal Injury System, Craig Hospital, Englewood, Colorado.ORCID https://orcid.org/0000-0003-0249-5353
Hannah K FandlIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Vinicius P GarciaIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Auburn R BerryIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Kendra N WegersonIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Emily I OstranderIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Hannah L CardenasIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Noah M DeSouzaIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Jared J GreinerIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.
Brian StaufferDivision of Cardiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Christopher A DeSouzaIntegrative Vascular Biology Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, Colorado.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim of this study was to determine whether circulating concentrations of activation- and apoptosis-derived endothelial cell-derived microvesicles (EMVs) differ between adults after subacute (time since injury ≤6 months) and chronic (time since injury >12 months) spinal cord injury (SCI). Methods: Peripheral blood was collected from 43 adults (age range 18-71 years): 12 non-injured adults (9 male/3 female), 16 adults with subacute cervical and high thoracic (C2-T3) motor complete injuries (13 male/3 female; time since injury 1-3 months), and 15 adults with chronic cervical and high thoracic (C1-T2) motor complete injuries (14 male/1 female; time since injury 12-52 months). EMVs were defined by markers of endothelial origin either by activation (CD62e

Indexed as

Cell-Derived MicroparticlesEndothelial CellsSpinal Cord InjuriesAdolescentAdultAgedApoptosisBiomarkersChronic DiseaseFemaleHumansMaleMiddle AgedYoung AdultBiomarkerscardiovascular diseaseendothelial microvesiclesspinal cord injury

Identifiers

PMID40585006
PMCPMC12199602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.