Evidence map›Paper›PMID 40584983›Full record

ArticleEJIFCC2025

Anti-NMDAR Autoimmune Encephalitis: A Diagnostic Challenge in Clinical Laboratories.

Patricia Ramos Mayordomo, Lourdes Martín Rodríguez, Nuria Alonso Castillejos

Abstract readCase Reports
In one paragraph

Article in EJIFCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patricia Ramos MayordomoDepartment of Clinical Analysis, Hospital Universitario Río Hortega, Valladolid, Castilla y León, Spain.
Lourdes Martín RodríguezDepartment of Clinical Analysis, Hospital Universitario Río Hortega, Valladolid, Castilla y León, Spain.
Nuria Alonso CastillejosDepartment of Clinical Analysis, Hospital Universitario Río Hortega, Valladolid, Castilla y León, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an antibody-mediated neurological disease which is acute, severe and with a complicated differential diagnosis. In 38% of cases, it arises as a paraneoplastic neurological syndrome (PNS) associated with cancer. Ovarian teratomas are the most frequently associated tumors, especially in young women. However, teratomas are usually mature and benign and psychiatric and neurological symptoms improve after resection. Clinical laboratories play a key role in the diagnosis and prognosis of these diseases, highlighting the importance of laboratory test results to prompt the search for the associated tumor. In addition, communication between laboratory medicine specialists and clinicians, as well as a multidisciplinary approach, are essential for early disease identification and treatment.

Indexed as

anti-NMDAR encephalitisautoimmune encephalitisautoimmunityimmunotherapyneuroimmunologyovarian teratoma

Identifiers

PMID40584983
PMCPMC12205148

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.