Evidence map›Paper›PMID 40584957›Full record

ReviewSkin health and disease2025

Insights into basal cell carcinoma with bone metastasis: a comprehensive review.

Azadeh Khayyat, Mohammad Ali Esmaeil Pour, Milad Moqadam, Seyed Amir Zohouri, Amir-Reza Khalili-Toosi, Amir Behzad Heidari, Parvaneh Hatami, Bruce R Smoller

Abstract readReview
In one paragraph

Review in Skin health and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Azadeh KhayyatDepartment of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID https://orcid.org/0000-0002-1867-1609
Mohammad Ali Esmaeil PourDepartment of Rheumatology, Augusta University Medical College of Georgia, Augusta, GA, USA.
Milad MoqadamDepartment of Family Medicine, BronxCare Health System, Bronx, NY, USA.
Seyed Amir ZohouriDepartment of Biology, Simon Fraser University Faculty of Science, Burnaby, BC, Canada.
Amir-Reza Khalili-ToosiDepartment of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.
Amir Behzad HeidariFamily Medicine, Essen Health Care, Bronx, NY, USA.
Parvaneh HatamiDepartment of Dermatology, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-3531-2907
Bruce R SmollerDepartment of Pathology, University of Rochester Medical Center, Rochester, NY, USA.ORCID https://orcid.org/0000-0002-7301-8274

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basal cell carcinoma (BCC), the most common skin cancer worldwide, is closely associated with sunlight exposure and generally exhibits a low metastatic potential, with a frequency ranging from 0.0028% to 0.55%. Despite its rarity, BCC with bony metastases causes important clinical complications. We collected information on published patients with a diagnosis of BCC with bony metastases, and examined patient demographics, tumour characteristics, histological features and treatment modalities to define patterns and outcomes. Our study encompassed 108 patients: 68 men and 40 women with a mean (SD) age of 66.9 (6.4) years. Histologically identified subtypes included 42 nodular, 28 infiltrative, 9 morphoeaform, 5 metatypical and 1 superficial BCC, with 23 patients having a mixed histopathology pattern. The main treatments were -surgery (

Identifiers

PMID40584957
PMCPMC12202874

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.