ArticleEuropean heart journal. Imaging methods and practice2025
Superior aortic strain and ventriculoarterial coupling in older women are moderately correlated with Framingham 10-year risk.
Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Heart Failure with Supranormal Ejection Fraction: An Emerging High-Risk Phenotype Within the Preserved Ejection Fraction Spectrum-A Systematic Review.Journal of clinical medicine · 2026Review
- Associations between echocardiographic parameters and aerobic performance in young athletes.PeerJ · 2026Article
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Authors and funding
9 authors.
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Abstract
Aims: Traditional risk factors do not fully characterize cardiovascular aging and are less helpful in assessing sex differences in cardiovascular risk. Using a novel cardiovascular magnetic resonance (CMR) method, we determined sex differences in aortic global longitudinal strain (AOGLS) and ventriculoarterial coupling (VAC) with correlations to Framingham risk scores. Methods and results: Community older adults without cardiovascular disease underwent CMR. AOGLS was the maximal absolute Lagrangian strain between the brachiocephalic artery and aortic annulus. VAC was aortic pulse wave velocity (AAPWV) divided by LVGLS. Among 202 participants (46.0% female, 70.2 ± 8.8 years), women had lower diastolic blood pressure (DBP) (70.5 ± 10.8 mmHg vs. 78.1 ± 9.5 mmHg, Conclusion: Novel CMR-derived aortic longitudinal strain differentiated ventriculo-aortic aging between the sexes. Women had superior AOGLS and VAC, independent of body size and DBP, that correlated better with Framingham risk scores compared to men. Impaired AOGLS and VAC may be useful in differentiating individuals at intermediate from low-borderline cardiovascular risk.
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