Evidence map›Paper›PMID 40584909›Full record

ArticleBioImpacts : BI2025

Stabilization of Hoogsteen H-bonds in G-quartet sheets by coordinated K

Abolfazl Barzegar, Nastaran Tohidifar

Abstract read
In one paragraph

Article in BioImpacts : BI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abolfazl BarzegarDepartment of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.ORCID https://orcid.org/0000-0002-1237-0848
Nastaran TohidifarResearch Center of Biosciences and Biotechnology (RCBB), University of Tabriz, Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: G-rich DNA nanomotors function as nanoscale devices and nanoswitches powered by the conversion of chemical energy into mechanical motion through transitions between duplex (DU) and tetraplex (TE) conformations. The stability of the TE conformation, crucial for nanomotor function, relies on G-quadruplex structures formed by guanine quartets. However, the detailed factors influencing TE stability remain unclear. Methods: This study investigated the role of coordinated K Results: The simulations revealed a clear dependence of G-quadruplex rigidity and TE conformation stability on the presence of coordinated K Conclusion: These findings demonstrate that coordinated K

Indexed as

DNA nanomotorG-quartetG-rich DNAHoogsteen H-bondsMD simulationTetraplex

Identifiers

PMID40584909
PMCPMC12204777

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.