SynthesisFrontiers in neuroscience2025
A systematic review and meta-analysis of acoustic stimulation in the treatment of insomnia.
Synthesis in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of sensory stimulation therapy in patients with sleep disorders: a scoping review.Frontiers in neuroscience · 2025Pooled it
- Brain dynamic audio stimulation for subjective sleep disturbances in healthcare professionals: a single-arm pilot feasibility study.Frontiers in neuroscience · 2026Article
- Randomized Controlled Trial of Acoustic Neuromodulation to Enhance Well-Being in Healthcare Workers.Global advances in integrative medicine and healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Insomnia is a prevalent and debilitating sleep disorder affecting approximately one-third of the global population, with 10-15% of individuals progressing to chronic insomnia. Acoustic stimulation, a promising non-pharmacological treatment, has gained significant attention due to its ability to improve sleep quality without the adverse effects of drugs. This study aims to evaluate the clinical efficacy of acoustic stimulation for treating insomnia through a systematic review and meta-analysis. Methods: We conducted a systematic search of both Chinese and English literature from PubMed, Embase, Web of Science, Cochrane, and Clinical Trials databases to identify randomized controlled trials (RCTs) evaluating acoustic stimulation for insomnia. The search period ranged from the establishment of the database to January 1, 2025. Two independent evaluators assessed study quality and extracted relevant data. Statistical analyses were conducted using RevMan 5.4 and Stata 18.0 software. Results: This meta-analysis includes 8 studies involving 419 patients. The results showed that acoustic stimulation significantly improved insomnia severity as evidenced by PSQI and ISI scores. Despite no significant improvement in sleep efficiency (SE) and Total sleep time (TST), acoustic stimulation notably increased total sleep time and alleviated insomnia symptoms. The test group demonstrated significant improvements compared to the control group, with the following outcomes: PSQI score [MD = -2.68, 95% CI (-3.35, -2.01), Conclusion: Acoustic stimulation is an effective and safe treatment for insomnia, offering significant improvements in sleep quality, severity, and overall health, with minimal side effects. It presents a promising alternative to traditional pharmacological treatments, especially for long-term use, and its clinical application has broad prospects. Future studies should focus on expanding sample sizes, exploring various stimulation methods, and considering individual patient characteristics for more detailed analyses. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42025632371, identifier CRD42025632371.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.