Evidence map›Paper›PMID 40584828›Full record

ArticleInternational journal of adolescence and youth2025

Loneliness in South African youth and its association with HIV infection, substance use and mental health.

Gabriella N Stein, Nicole Phillips, Mothabisi N Nyathi, Jacqueline Hoare

Abstract read
In one paragraph

Article in International journal of adolescence and youth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriella N SteinDepartment of Psychiatry and Mental Health, Neuroscience Institute, University of Cape Town, South Africa.
Nicole PhillipsDepartment of Psychiatry and Mental Health, Neuroscience Institute, University of Cape Town, South Africa.
Mothabisi N NyathiDepartment of Paediatrics & Child Health and SA- MRC unit on Child & Adolescent Health, University of Cape Town, South Africa.
Jacqueline HoareDepartment of Psychiatry and Mental Health, Neuroscience Institute, University of Cape Town, South Africa.

Funding

Cape Town Adolescent Antiretroviral Cohort- Substance, Imaging, Mental Health (CTAAC-SIM)R61DA053736 · NIDA · UNIVERSITY OF CAPE TOWN · PI HOARE, JACQUELINE · 2021 to 2023
$1.1M
Cape Town Adolescent Antiretroviral Cohort- Substance, Imaging, Mental Health (CTAAC-SIM)R33DA053736 · NIDA · UNIVERSITY OF CAPE TOWN · PI HOARE, JACQUELINE · 2024 to 2025
$945k
NIDA NIH HHS R33 DA053736NIDA NIH HHS R61 DA053736
6 · The paper itself

Abstract

Youth are susceptible to experiencing loneliness, which is associated with poor mental health and substance use. However there are limited data from low-middle-income settings especially in youth living with HIV. This study investigated loneliness in South African youth and association with perinatal HIV infection (PHIV), mental health and substance use. A cross-sectional descriptive exploratory study of youth with PHIV and HIV negative youth 17 to 24 years was conducted measuring loneliness and associations with depression, anxiety, post-traumatic stress disorder (PTSD), trauma exposure, coping, resilience and substance use. Of 122 youth, a moderate to high degree of loneliness was found in 92.6%. Loneliness was associated with female sex, depression, anxiety, PTSD, negative coping, lower levels of resilience and exposure to trauma. Loneliness was not associated with PHIV or substance use. Given the high levels of loneliness, peer-based interventions for youth aimed at improving social support, depression and anxiety should be strengthened.

Indexed as

HIVlonelinessmental healthSouth Africasubstance useyouth

Identifiers

PMID40584828
PMCPMC12199308

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.