ArticleInternational journal of nanomedicine2025
Clustered, SERS-Active, Ultrasmall AuNPs for Photothermal Therapy.
Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- A Renally Excretable Gold Nanoparticle Oncology Platform Enabling Effective Photothermal Therapy and Chemotherapy Combination.ACS nano medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Gold nanoclusters (AuNCs) have emerged as promising agents for photothermal cancer therapy due to their unique optical properties and potential for tumour targeting. Methods: In this study, we developed clustered, excretable AuNCs using a glycol chitosan derivative (GCPQ) and investigated their physicochemical properties, photothermal effect, and therapeutic efficacy. Results: The AuNCs exhibited tunable surface plasmon resonance peaks dependent on the polymer:AuNP ratio, with optimized clusters showing surface enhanced Raman scattering and photothermal heating. In vivo studies in a mouse tumour model demonstrated significant tumour growth inhibition (334% growth vs 607% growth for untreated animals after 6 days) when combining intratumoural AuNC injection with near-infrared laser irradiation. Conclusion: The results provide proof-of-concept for the potential of these AuNCs in photothermal cancer therapy. Future work should focus on improving tumour targeting, optimizing treatment parameters, and assessing long-term safety to advance this platform toward clinical translation.
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Registered trials
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