Evidence map›Paper›PMID 40584720›Full record

ArticleJHLT open2025

Invasive surgical site infections after lung transplantation: contemporary risk factors and associated clinical outcomes.

Manuela Carugati, Sana Arif, John Michael Reynolds, John Carroll Haney, Michael Edwards Yarrington, Katherine Young, Deepika Kulkarni, Alzora Benjamin, Katina Walline, Jonathan Huggins and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Manuela CarugatiDepartment of Medicine, Division of Infectious Diseases, Duke University, Durham, NC.
Sana ArifDepartment of Medicine, Division of Infectious Diseases, Duke University, Durham, NC.
John Michael ReynoldsDepartment of Medicine, Division of Pulmonology, Duke University, Durham, NC.
John Carroll HaneyDepartment of Surgery, Division of Cardiothoracic Surgery, Duke University, Durham, NC.
Michael Edwards YarringtonDepartment of Medicine, Division of Infectious Diseases, Duke University, Durham, NC.
Katherine YoungDepartment of Medicine, Division of Pulmonology, Duke University, Durham, NC.
Deepika KulkarniDepartment of Medicine, Division of Pulmonology, Duke University, Durham, NC.
Alzora BenjaminDepartment of Medicine, Division of Pulmonology, Duke University, Durham, NC.
Katina WallineDepartment of Medicine, Division of Pulmonology, Duke University, Durham, NC.
Jonathan HugginsDepartment of Medicine, Division of Infectious Diseases, Duke University, Durham, NC.
Morgan RosserDepartment of Anesthesiology, Division of Cardiothoracic Anesthesiology, Duke University, Durham, NC.
Samantha MorrisonDepartment of Biostatistics & Bioinformatics, Duke University School of Medicine, Durham, NC.
Sarah PeskoeDepartment of Biostatistics & Bioinformatics, Duke University School of Medicine, Durham, NC.
Brandi Ann BottigerDepartment of Anesthesiology, Division of Cardiothoracic Anesthesiology, Duke University, Durham, NC.
Rachel Ann MillerDepartment of Medicine, Division of Infectious Diseases, Duke University, Durham, NC.
Barbara Dudley AlexanderDepartment of Medicine, Division of Infectious Diseases, Duke University, Durham, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive primary surgical site infections (IP-SSI) complicate lung transplant (LT) surgery. Identification of IP-SSI risk factors is critical to IP-SSI prevention. Methods: This single-center retrospective cohort study of adult patients who underwent LT at Duke University over a 5-year period (2017-2021) aimed to identify IP-SSI risk factors and describe outcomes associated with IP-SSI diagnosis. IP-SSI risk factors were identified using a Least Absolute Shrinkage and Selection Operator procedure for logistic regression. Results: IP-SSI occurred in 74/568 (13.0%) LT recipients. Restrictive lung disease, donor positive respiratory or blood cultures, operative time, post-transplant thoracic re-operation within 90 days of transplant, and ECMO by day 3 post-transplant were positively associated with IP-SSI. Obstructive lung disease, primary closure, and enhanced immunosuppression within 90 days of transplant were negatively associated with IP-SSI. Patients with IP-SSI were descriptively characterized by longer index transplant hospitalizations (92 Conclusions: Conservative surgical approaches, targeted antimicrobial prophylaxis, and increased surveillance for patients with IP-SSI risks may play a critical roleto limit IP-SSI in the LT population.

Indexed as

Antimicrobial prophylaxisInfectionsLung transplantLung transplantationSurgical site infections

Identifiers

PMID40584720
PMCPMC12205819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.