Evidence map›Paper›PMID 40584693›Full record

ReviewThe Lancet regional health. Southeast Asia2025

Financial toxicity of hemophilia care in Southeast Asian countries.

Jose Marco Antonio, Stephanie Wang, Frederic Ivan L Ting, Jeremiah R Vallente, Edward Christopher Dee, Erin Jay G Feliciano

Abstract readReview
In one paragraph

Review in The Lancet regional health. Southeast Asia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The Dilemma of Providing Advanced Hemophilia Treatments in Developing Countries - For Whom, by Whom and Where?Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jose Marco AntonioHarvard University, Cambridge, MA, USA.
Stephanie WangHarvard University, Cambridge, MA, USA.
Frederic Ivan L TingSection of Medical Oncology, Department of Internal Medicine, Corazon Locsin Montelibano Memorial Regional Hospital, Bacolod, Philippines.
Jeremiah R VallenteDepartment of Internal Medicine, Quirino Memorial Medical Center, Quezon City, Philippines.
Edward Christopher DeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Erin Jay G FelicianoSchool of Medicine and Public Health, Ateneo de Manila University, Pasig City, Philippines.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Hemophilia is a rare, chronic bleeding disorder with high treatment costs that pose significant economic challenges, particularly in many countries of Southeast Asia (SEA), where disease burden is disproportionately high. In this commentary, we explore the drivers of financial toxicity (FT) in hemophilia care across SEA. We identify key contributors including inadequate health insurance coverage, reliance on unstable humanitarian aid, geographic disparities in care access, and cultural factors that place financial and emotional strain on families. Despite some policy efforts-such as universal health coverage and national cancer control plans-systemic gaps in financing, infrastructure, and provider distribution persist. We propose actionable steps using the social ecological model of health to reduce FT at the individual, interpersonal, community, and policy levels, including expanded insurance coverage, decentralized care, telehealth access, financial navigation services, and public education. Addressing the multifactorial nature of FT is essential to improving quality of life and equity in care for patients with hemophilia in SEA.

Indexed as

Benign hematologyFinancial toxicityHemophiliaSoutheast Asia

Identifiers

PMID40584693
PMCPMC12205610

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.