ArticleEuropean heart journal open2025
Enhanced ventricular synchrony and myocardial function with bipolar left bundle area pacing: a comparative study of anodal ring capture versus unipolar pacing.
Article in European heart journal open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: Cardiac pacing aims to replicate physiological heart rhythm. While left bundle area pacing (LBAP) enhances left ventricular (LV) activation, it often struggles to fully address interventricular dyssynchrony. Bipolar LBAP with anodal ring capture (LBAP-ARC) offers a potential solution by synchronously activating both left and right bundle branches. This study aims to compare the effects of unipolar LBAP and LBAP-ARC on ventricular synchrony and myocardial function. Methods and results: A prospective cohort study was conducted with enroling 32 patients undergoing successful LBAP implantation. Pacing thresholds, lead impedance, QRS duration, and echocardiographic parameters-including LV and right ventricular (RV) global longitudinal strain (GLS), systolic dyssynchrony index, and interventricular mechanical delay (IVMD)-were assessed under unipolar LBAP and LBAP-ARC configurations. Left bundle area pacing with anodal ring capture significantly improved LV GLS (-16.09% vs. -14.85%, Conclusion: Left bundle area pacing with anodal ring capture enhances ventricular synchrony and improves subclinical myocardial function compared to unipolar LBAP, establishing itself as a promising approach in physiological cardiac pacing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.