ArticleMayo Clinic proceedings. Innovations, quality & outcomes2025
Nailfold Video Capillaroscopy in Acute and Chronic Skin Graft Versus Host Disease.
Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Objective: To assess the utility of nailfold video capillaroscopy (NVC) in patients diagnosed with acute and chronic graft versus host disease (GVHD) of the skin. Patients and Methods: Patients diagnosed with acute and chronic skin GVHD (n=11) and those without the diagnosis of GVHD (controls) (n=21) underwent NVC to assess capillary density, morphology, and hemorrhage. Statistical comparisons were made using Fisher's exact test. The study was performed from March 1, 2024, to August 1, 2024. Results: Patients diagnosed with acute and chronic GVHD were observed to have considerably more microhemorrhages, ramifications, and disorganized capillaries when compared with patients without a diagnosis of acute or chronic GVHD. Conclusion: This study reveals significant NVC abnormalities in patients with GVHD, suggesting distinct microvascular features that imply potential diagnostic value. The NVC may be a valuable tool for diagnosing and monitoring GVHD and warrants further investigation in larger cohorts.
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