Evidence map›Paper›PMID 40584522›Full record

SynthesisFrontiers in neurology2025

Bibliometric and visualization analysis of glioma pharmacotherapy from 2020 to 2024.

Xinjie Hong, Zhentao Wei, Tian Zuo, Liyu Xu, Haohang Zhang, Tao Xu, Dongmei Wang, Chengyin Lu, Lijun Hou

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinjie Hong *Department of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Zhentao Wei *Department of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Tian Zuo *Department of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Liyu XuDepartment of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Haohang ZhangDepartment of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Tao XuDepartment of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Dongmei WangDepartment of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Chengyin LuDepartment of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Lijun HouDepartment of Neurosurgery, The Second Affiliated Hospital of Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Gliomas are the most common and aggressive malignant tumors of the central nervous system. Their complex biology and adaptive resistance mechanisms pose major obstacles to existing treatment strategies. This study aims to analyze research published over the past 5 years to identify emerging trends, effective therapeutic agents, and novel treatment strategies. Methods: Relevant articles on glioma drug therapy were retrieved from the Web of Science Core Collection for the period 2020-2024. Bibliometric analyses were performed using CiteSpace and VOSviewer to examine authorship, institutional and national contributions, journal impact, and keyword distributions. A total of 9,701 articles were included in the analysis. Results: China leads in publication volume on glioma research, followed by the United States. Liu Yang from China is the most prolific author in this field over the past 5 years. Institutions from China and the United States are the primary contributors to this area of research. Bibliometric analysis identified four major thematic clusters: glioma treatment, drug delivery, immunotherapy and the tumor microenvironment, and the molecular mechanisms underlying glioma cell behavior. Conclusion: This systematic analysis of glioma treatment research over the past 5 years highlights key global research hotspots and emerging trends. Drug delivery and immunotherapy have gained increasing attention as promising therapeutic approaches. Advances in glioma treatment are expected to improve patient outcomes.

Indexed as

bibliometric analysisgliomapharmacotherapyresearch trendstreatment strategies

Identifiers

PMID40584522
PMCPMC12202528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.