Phosphorylation of the fission protein Drp1 contributes to the impact of the curcuminoid 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one on mitochondrial and cellular processes.

Navyamol Chakkalaparambil Dileep, Chi-Wei Chiu, Ching-Tse Wu, Chuang-Rung Chang, Chih-Yu Lo

Abstract read

In one paragraph

Article in BBA advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Curcumin and Its Derivatives as Anticancer Agents in Head and Neck Cancer: Molecular Mechanisms and Preclinical Evidence.International journal of molecular sciences · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Navyamol Chakkalaparambil DileepInstitute of Biotechnology, College of Life Science and Medicine, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu City 300044, Taiwan.

Chi-Wei ChiuInstitute of Biotechnology, College of Life Science and Medicine, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu City 300044, Taiwan.

Ching-Tse WuInstitute of Biotechnology, College of Life Science and Medicine, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu City 300044, Taiwan.

Chuang-Rung ChangInstitute of Biotechnology, College of Life Science and Medicine, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu City 300044, Taiwan.

Chih-Yu LoDepartment of Food Science, National Chia-Yi University, 300 Syuefu Rd., Chiayi City 600355, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin and its curcuminoid derivatives extracted from turmeric have been investigated for their potential therapeutic benefits in cancer treatment. Curcuminoids 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one and bisdemethoxycurcumin can be obtained from

Indexed as

1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-oneCurcuminCurcuminoidDrp1Mitochondria

Identifiers

PMID40584520

DOI10.1016/j.bbadva.2025.100164

PMCPMC12206055

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.