ArticlePlastic and reconstructive surgery. Global open2025
Latissimus Dorsi Flap for Chemotherapy-induced Extensive Forearm Necrosis: Case Study.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Chemotherapeutic drug extravasation represents one of the most prevalent complications encountered during chemotherapy administration in oncology patients. A severe consequence of this complication is the induction of extensive soft-tissue necrosis, for which a definitive clinical management protocol remains elusive. This study presented and analyzed a case of an older male patient who developed extensive soft-tissue necrosis in the forearm due to chemotherapeutic drug extravasation, prompting his admission to our department for treatment. The patient underwent repeated debridement procedures, followed by the application of a latissimus dorsi myocutaneous flap combined with skin grafting to cover the wound surface. A 2-month postoperative follow-up revealed satisfactory growth of both the flap and skin graft. This flap transfer technique offers a novel therapeutic approach for the management of extensive soft-tissue necrosis resulting from chemotherapeutic drug extravasation.
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