ArticleWorld journal of gastrointestinal surgery2025
Remission of type 2 diabetes one year after esophagectomy with gastric conduit reconstruction: A prospective cohort study.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundType 2 diabetes (T2D) remission has been widely reported after bariatric surgery, but rarely reported after esophagectomy.
aimTo explore the incidence and predictors of T2D remission 1 year after esophagectomy with gastric conduit reconstruction.
methodsIn this prospective study, consecutive patients from 2 tertiary hospitals who had esophageal cancer and T2D and underwent esophagectomy with gastric conduit reconstruction were studied preoperatively and at 3 months, 6 months, and 12 months postoperatively. Remission of T2D is defined as glycated hemoglobin (HbA1c) values below 6.5% without glucose-lowering medications. Related clinical information were recorded and analyzed.
resultsA total of 187 patients were included. Of these patients, 24 (12.8%) discontinued antidiabetic drugs and maintained HbA1c values below 6.5% 1 year after surgery. At baseline, patients with T2D remission were younger (63.0 ± 5.2 years
conclusionThis study reveals a significant incidence of T2D remission after esophagectomy with gastric conduit reconstruction, and remission is more frequent in patients with younger age and greater body weight.
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