ArticleWorld journal of gastrointestinal surgery2025
Ultrasound elastography for the differential diagnosis of benign and malignant gastrointestinal stromal tumors.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPreoperative distinguishing between benign and malignant gastrointestinal stromal tumors (GISTs) poses a challenge. Ultrasound elastography has emerged as a promising diagnostic tool; however, further investigation is needed to assess its diagnostic accuracy in evaluating GISTs.
aimTo evaluate the accuracy of ultrasound elastography for differentiating between benign and malignant GISTs.
methodsThis prospective study included 110 patients with 103 histopathologically confirmed GISTs between January 2021 and December 2023. All tumors underwent conventional ultrasound examination, strain elastography (SE), and shear-wave elastography (SWE) before surgical resection. The study evaluated elastographic parameters such as strain ratio, elastographic patterns, mean elastic modulus, and heterogeneity index. Diagnostic performance was evaluated using receiver operating characteristic curve analysis, with histopathological diagnosis as the reference standard.
resultsOf the 103 GISTs, 45 (43.7%) were benign and 58 (56.3%) were malignant based on modified National Institutes of Health criteria. Malignant GISTs exhibited significantly higher strain ratios (4.82 ± 1.73
conclusionUltrasound elastography shows high diagnostic accuracy in distinguishing between benign and malignant GISTs. Combining SE and SWE provides complementary parameters for preoperative risk stratification.
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