ArticleSSM - population health2025
Cumulative neighborhood disadvantage and racial and geographic disparities in epigenetic aging.
Article in SSM - population health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Neighborhood disadvantage and accelerated epigenetic aging in the early aftermath of trauma: The moderating role of individual psychological resources.Journal of psychiatric research · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
Living in a socioeconomically disadvantaged neighborhood is associated with worse health. However, the biological pathways underpinning this association remain unclear. Using 1388 adults from Researching Epigenetics, Weathering and Residential Disadvantage (REWARD), an ancillary study to the Survey of the Health of Wisconsin (SHOW), we examined the contribution of cumulative neighborhood disadvantage across the life course to racial and geographic disparities in epigenetic markers of biological aging. Results showed that urban Black adults experienced faster epigenetic aging than urban, suburban, and rural White adults across three epigenetic aging clocks. Approximately 37 % (GrimAge), 70 % (DunedinPACE), and 100 % (PhenoAge) of the White-urban Black disparities in epigenetic age acceleration were explained by differential exposure to cumulative neighborhood disadvantage over the life course. Interactions testing differential susceptibility to neighborhood disadvantage by race were not significant. In summary, differential exposure to cumulative neighborhood disadvantage over the life course, rather than differential biological response to these exposures, shapes racial and geographic disparities in epigenetic aging.
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