ReviewFrontiers in molecular neuroscience2025
Roles of ERK signaling pathway in regulating myelination of the peripheral nervous system.
Review in Frontiers in molecular neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Control of Schwann Cell Myelination by DDR1 Receptor Tyrosine Kinase.International journal of molecular sciences · 2026Article
- Repetitive transcranial magnetic stimulation suppresses glia-associated neuroinflammation and promotes peripheral nerve recovery in neuropathic pain.Frontiers in immunology · 2026Article
- Molecular Frameworks for ERK1/2 Inhibition: Lessons from Synthetic and SAR Explorations.ACS omega · 2025Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myelination of Schwann cells is a complex biological process that plays a crucial role in peripheral nervous system (PNS) development and repair. Recent studies have indicated that the extracellular signal-related kinase (ERK) signaling pathway participates in both developmental PNS myelination and remyelination. This review focuses on recent evidence identifying the roles of the ERK signaling pathway in regulating Schwann cell differentiation, myelination, and remyelination. In addition, the crosstalk between the ERK signaling pathway and other cellular signaling pathways that control Schwann cell myelination, such as c-Jun and Notch, are discussed. This review provides an overview of recent studies, revealing that dysregulated expression of the ERK signaling pathway participated in the pathogenesis of hereditary and acquired peripheral neuropathies.
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