Evidence map›Paper›PMID 40584383›Full record

ArticleACS omega2025

Synthesis and Characterization of Q0-Eugenol Nanoemulsion for Drug Delivery to Breast and Hepatocellular Cancer Cell Lines.

Naghmeh Abbasi, Mostafa Shourian, Mohammad Hassan Shahavi

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Naghmeh AbbasiDepartment of Biology, Faculty of Sciences, University of Guilan, 4193833697 Rasht, Iran.ORCID https://orcid.org/0009-0005-3420-3927
Mostafa ShourianDepartment of Biology, Faculty of Sciences, University of Guilan, 4193833697 Rasht, Iran.ORCID https://orcid.org/0000-0002-5132-297X
Mohammad Hassan ShahaviDepartment of Nanotechnology, Faculty of Engineering Modern Technologies, Amol University of Special Modern Technologies (AUSMT), 4615664616 Amol, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the second cause of death globally. The advent of nanoparticles has revolutionized drug delivery in cancer treatment. This study introduces a novel Q0-eugenol nanoemulsion designed for enhanced drug delivery. Synthesis of nanoemulsion was performed by the homogenization technique and ultrasonication for size reduction. DLS, FTIR, and UV-vis spectroscopy were used for characterization of Q0-eugenol nanoemulsion. MTT assay and flow cytometry assay were applied to determine the fibroblast, KPL1, and PLC/PRF/5 cell lines to consider the cell viability and apoptosis percentage, respectively. The oxidative status of Q0-eugenol nanoemulsion was evaluated by the ferric reducing antioxidant power assay and the thiobarbituric acid reactive substance assay. The zeta potential charge of eugenol and Q0-eugenol nanoemulsion formulation was equal to 45.1 and 22.7 mV, respectively. Eugenol nanoemulsion and Q0-eugenol nanoemulsion treatment exhibited antiproliferative effect against breast and liver cancer cell lines (

Identifiers

PMID40584383
PMCPMC12198986

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.