Evidence map›Paper›PMID 40584331›Full record

ArticleACS omega2025

Rational Design of Antimicrobial Peptides Based on Bacterial Type‑I Toxins AapA1, IbsC, and Fst1.

Emma Dyhr, Ingvill Pedersen Sæbo̷, Ida Mathilde Marstein Riisnæs, Magnar Bjo̷rås, Emily Helgesen, James Alexander Booth, Henrik Franzyk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma DyhrDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark.ORCID https://orcid.org/0009-0008-1806-0761
Ingvill Pedersen Sæbo̷Department of Microbiology, Oslo University Hospital and the University of Oslo, Rikshospitalet, 0373 Oslo, Norway.
Ida Mathilde Marstein RiisnæsDepartment of Microbiology, Oslo University Hospital and the University of Oslo, Rikshospitalet, 0373 Oslo, Norway.
Magnar Bjo̷råsDepartment of Microbiology, Oslo University Hospital and the University of Oslo, Rikshospitalet, 0373 Oslo, Norway.
Emily HelgesenDepartment of Microbiology, Oslo University Hospital and the University of Oslo, Rikshospitalet, 0373 Oslo, Norway.
James Alexander BoothDepartment of Microbiology, Oslo University Hospital and the University of Oslo, Rikshospitalet, 0373 Oslo, Norway.
Henrik FranzykDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-2822-1927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antibacterial properties of 43 modified peptide toxins derived from three distinct type-I toxin-antitoxin (TA) systems, comprising

Identifiers

PMID40584331
PMCPMC12199084

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.