ArticleACS omega2025
Surface Modification of Biochar to Prepare Environmentally Friendly Electrochemical Biosensors for Detection of Cardiac Troponin T.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Click-Functionalized Biochar as a Spacer-Engineered Interface for Electrochemical Biosensing.ACS omega · 2026Article
- From Biomass Waste to Multifunctional Biochar: Tailored Preparation and Emerging Applications in Energy, Environment, and Sensing.Molecules (Basel, Switzerland) · 2026Review
- Sustainable char production from pyrolysis of refuse-derived fuel for nitrate removal from water.Scientific reports · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Driven by the need to investigate enhanced biosensing properties alongside the development of low-toxicity, economical, eco-friendly, and sustainable materials, this work explores the functionalization of biochara carbon-based materialand its subsequent anchoring onto the working electrode for the detection of cardiac troponin T (cTnT). Here, we discuss the interaction between biochar and glutaraldehyde at various concentrations, aiming to elucidate the relationship between the formation of full acetals and hemiacetals. It first allows an understanding of the cross-link reactions between glutaraldehyde and biochar and then better anchoring with the Cystamine-Au working electrode of a printed circuit board (PCB). These aspects improve the biosensor's stability and the cTnT antibody's specific adsorption. Electrochemical, AFM, Fluorescence Confocal, SEM, and FTIR analyses were employed to identify the optimal glutaraldehyde concentration that maximizes hemiacetal group formation, critical for stability to the electrode and the specific adsorption of the antibody. The resulting label-free, direct electrochemical cTnT immunosensor showed high sensitivity and selectivity, with a detection capacity of 0.01-5.00 ng·mL
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Registered trials
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