ArticleClinical ophthalmology (Auckland, N.Z.)2025
Evaluating the Predictive Accuracy of an AI-Based Tool for Postoperative Vault Estimation in Phakic Intraocular Lens Implantation.
Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- AI-Assisted UBM versus Conventional Sizing Approaches for ICL Implantation: A Retrospective Analysis of Vault Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Retrospective Validation of an AI Based Tool for Vault Prediction After Implantable Collamer Lens Surgery for High Myopia.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Real-World Safety Profile of EVO and EVO+ Implantable Collamer Lenses: A Retrospective Study Based on FDA Surveillance Data.Ophthalmology and therapy · 2025Article
- Artificial intelligence for posterior capsule opacification.Frontiers in medicine · 2025Review
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9 authors.
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Abstract
Introduction: Phakic intraocular lenses are widely used for refractive error correction, with the EVO ICL delivering excellent visual outcomes. Achieving an optimal postoperative vault is critical to minimize complications. The purpose of this study was to evaluate the predictive accuracy of an AI-based tool that integrates high-resolution ultrasound biomicroscopy (UBM) imaging with biometric data, for estimating postoperative vault in myopic patients. Settings: The study was performed at four centers: Instituto Zaldivar (Argentina), Wellington Eye Clinic (Ireland), Medipolis Eye Center (Belgium), and Asian Eye Institute (Philippines). Methods: In this retrospective, multicenter study, 347 eyes from 228 myopic patients (mean age 31.3 ± 7.7 years) underwent ICL implantation. Preoperative biometric parameters and UBM imaging were utilized to generate vault predictions using the AI-based tool. Predicted vault values were compared with clinical measurements obtained at 1 day and 1 month postoperatively. Statistical analyses, including Spearman correlation and multivariable linear regression, were conducted to assess the agreement between predicted and measured vaults and to identify significant predictive factors. Results: At 1 day postoperatively, the mean clinical vault was 520.97 ± 178.73 μm versus a predicted vault of 508.16 ± 163.00 μm, with a mean signed difference of -12.81 μm (r²=0.621, p<0.001). Subgroup analyses across the four centers demonstrated stable predictions, with no significant inter-center differences in either clinical or predicted vault measurements (p>0.05). Multivariable regression identified ARise and spherical power as significant predictors of vault discrepancy, with uniform effects across diverse populations. Conclusion: The ICLGuru™ reliably predicts postoperative vault with clinically acceptable accuracy. These findings underscore the generalizability and reliable performance of the AI-based tool across varied clinical settings. Its integration into preoperative planning may enhance ICL sizing and reduce complications in myopic patients.
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