Trial reportNeuropsychiatric disease and treatment2025
An Evaluation a PrEP-Focused HIV Prevention Intervention Tailored for Individuals with Opioid Use Disorder and Cognitive Dysfunction.
Trial report in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Purpose: This study aimed to test the efficacy of the 4-week Bio-behavioral Community-Friendly Health Recovery Program (CHRP-BB) at improving HIV prevention outcomes among individuals receiving medication for opioid use disorder (MOUD) and to examine the extent to which cognitive dysfunction impacts outcomes. Patients and Methods: This randomized controlled trial included 237 individuals receiving MOUD and Pre-Exposure Prophylaxis (PrEP) in New Haven, CT. We conducted a longitudinal regression analysis to evaluate the impact of the intervention on HIV risk behaviors and PrEP-related outcomes over time. We estimated the effect of treatment on the outcome variables that include PrEP knowledge and adherence skills, HIV risk behavior, Syringe cleaning skills, and Condom skills using a difference-in-differences framework across four time periods (Post-intervention, and 3-, 6-, and 9-month follow-ups). Results: The CHRP-BB intervention exerted a positive effect on experimental group participants across a range of key outcomes, particularly among shorter term IDUs. Improvements that were the most pronounced included PrEP outcomes (knowledge and adherence skills) and syringe cleaning skills. Most outcomes were not significantly disrupted by cognitive dysfunction. Conclusion: Outcomes from this trial highlight the efficacy of the CHRP-BB intervention, including the use of cognitive dysfunction compensatory strategies, to significantly improve HIV prevention efforts among individuals on MOUD. We suggest that future efforts focus on refining and testing additional strategies that can further optimize intervention effects across a broader range of outcomes and MOUD patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.