Evidence map›Paper›PMID 40584204›Full record

ReviewTaiwan journal of ophthalmology

Current understanding of ocular fluid analysis in uveitis.

Mariko Shirane, Nobuyo Yawata, Koh-Hei Sonoda

Abstract readReview
In one paragraph

Review in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mariko ShiraneDepartment of Ophthalmology, Graduate School of Medical Science, Kyushu University, Fukuoka.
Nobuyo YawataDepartment of Ocular Pathology and Imaging Science, Kyushu University, Fukuoka, Japan.
Koh-Hei SonodaDepartment of Ophthalmology, Graduate School of Medical Science, Kyushu University, Fukuoka.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uveitis sometimes causes severe inflammation and significant loss of visual function. However, the cause is unknown in approximately 50% of cases, and the pathogenesis of the disease is also unknown in many cases. Intraocular fluid is rich in biological substances such as DNA/RNA, cytokines, antibodies, proteins, and metabolites and analysis of intraocular fluid is important for identifying biomarkers and understanding the pathogenesis of uveitis. For example, comprehensive polymerase chain reaction test of intraocular fluid has enabled rapid diagnosis of infectious uveitis. In addition, a combination of histopathological examination of intraocular fluid, cytokine measurement, flow cytometry, and genetic assessments has increased the efficiency of diagnosis of intraocular malignant lymphoma. In recent years, omics analysis such as metabolomics, proteomics, and transcriptomics has been actively conducted in the medical field, and there are scattered reports of intraocular fluid analysis in uveitis. Moreover, research and practical application of artificial intelligence (AI) is also progressing rapidly in the medical field. In the field of ophthalmology, many studies introducing AI have been reported, and a small number of machine learning studies using intraocular fluid have also been reported. In this review, we searched PubMed for previous reports on intraocular fluid analysis in uveitis and aim to introduce the analysis of intraocular fluid in uveitis, including the results of our comprehensive genetic analysis of cytomegalovirus in the eye.

Indexed as

Artificial intelligenceintraocular fluid analysisomics analysispolymerase chain reaction testuveitis

Identifiers

PMID40584204
PMCPMC12204668

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.