Evidence map›Paper›PMID 40584128›Full record

ArticleVeterinary world2025

Protective effect of purple sweet potatoes (

Carmen R Silva-Correa, Julio Hilario-Vargas, Abhel A Calderón-Peña, Víctor E Villarreal-La Torre, Cinthya L Aspajo-Villalaz, Natalia Bailon-Moscoso, Juan Carlos Romero-Benavides, Oscar Herrera-Calderon, William A Sagástegui-Guarniz, Julio A Castañeda-Carranza and 2 more

Abstract read
In one paragraph

Article in Veterinary world, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carmen R Silva-CorreaDepartment of Pharmacology, Faculty of Pharmacy and Biochemistry, National University of Trujillo, Trujillo, Perú.
Julio Hilario-VargasDepartment of Human Physiology, Faculty of Medicine, National University of Trujillo, Trujillo, Perú.
Abhel A Calderón-PeñaDepartment of Biological Chemistry and Animal Physiology, Faculty of Biological Sciences, National University of Trujillo, Trujillo, Perú.
Víctor E Villarreal-La TorreDepartment of Pharmacology, Faculty of Pharmacy and Biochemistry, National University of Trujillo, Trujillo, Perú.
Cinthya L Aspajo-VillalazDepartment of Biological Chemistry and Animal Physiology, Faculty of Biological Sciences, National University of Trujillo, Trujillo, Perú.
Natalia Bailon-MoscosoDepartamento de Ciencias de la Salud, Facultad de Ciencias de la Salud, Universidad Técnica Particular de Loja, Loja, Ecuador.
Juan Carlos Romero-BenavidesDepartamento de Química, Facultad de Ciencias Exactas y Naturales, Universidad Técnica Particular de Loja, Loja, Ecuador.
Oscar Herrera-CalderonDepartment of Pharmacology, Bromatology and Toxicology, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Jr Puno 1002, Lima 15001, Peru.
William A Sagástegui-GuarnizDepartment of Pharmacology, Faculty of Pharmacy and Biochemistry, National University of Trujillo, Trujillo, Perú.
Julio A Castañeda-CarranzaDepartment of Statistics, Faculty of Physical and Mathematical Sciences, National University of Trujillo, Trujillo, Perú.
Walter E Janampa-CastilloDepartment of Psychological Sciences, Faculty of Education and Communication Sciences, National University of Trujillo, Trujillo, Perú.
José L Cruzado-RazcoDepartment of Pharmacology, Faculty of Pharmacy and Biochemistry, National University of Trujillo, Trujillo, Perú.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Breast cancer is one of the most prevalent and lethal malignancies affecting women worldwide. Given the limitations of conventional treatments, there is an increasing interest in exploring naturally derived compounds with chemoprotective properties. Purple sweet potatoes ( Materials and Methods: Fifty female Results: The extract exhibited significant antioxidant activity comparable to quercetin at 1500 ppm (DPPH assay) and a high anthocyanin content (138.92 ± 0.58 mg/100 g dry extract). Tumor latency was significantly prolonged in the 600 mg/kg group (101 days) compared to the DMBA control (88 days). In addition, this group showed a marked reduction in tumor volume (2.26 cm Conclusion: The ethanolic extract of purple sweet potato peels demonstrated a dose-dependent chemopreventive effect against DMBA-induced breast cancer in rats. The extract's high anthocyanin content likely contributed to its antioxidant and antitumor activities. These findings suggest potential applications in dietary chemoprevention, warranting further investigation into its molecular mechanisms and clinical translation.

Indexed as

7,12-dimethylbenz(a)anthraceneanthocyaninsantioxidant activitybreast cancerIpomoea batatastumor latency

Identifiers

PMID40584128
PMCPMC12205227

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.