Evidence map›Paper›PMID 40583999›Full record

ArticleJAC-antimicrobial resistance2025

Over-the-counter antimicrobial dispensing in Lusaka Province retail pharmacies, Zambia.

Kelly Chisanga, Ernest Simpemba, Chipwaila Chunga, Victor Chalwe, Otridah Kapona, Winfredah Nyirenda, James Mwansa, Godfrey Biemba

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelly ChisangaDirectorate of Research and Postgraduate Studies, Levy Mwanawasa Medical University, P. O. Box 33991, Lusaka, Zambia.ORCID https://orcid.org/0000-0002-7628-3241
Ernest SimpembaDepartment of Pharmaceutics and Pharmacognosy, Faculty of Pharmacy, Lusaka Apex Medical University, P. O. Box 31909, Lusaka, Zambia.
Chipwaila ChungaNational Health Research Authority, Department of Research Regulation and Promotion, Lot No. 18961/M in Libala South, Off Kasama Road, P. O. Box 30075, Lusaka, Zambia.
Victor ChalweNational Health Research Authority, Department of Research Regulation and Promotion, Lot No. 18961/M in Libala South, Off Kasama Road, P. O. Box 30075, Lusaka, Zambia.
Otridah KaponaNational Public Health Reference Laboratories, Zambia National Public Health Institute, Stand No. 1186, Corner of Chaholi & Addis Ababa Roads, Rhodes Park, Lusaka, Zambia.
Winfredah NyirendaNational Health Research Authority, Department of Research Regulation and Promotion, Lot No. 18961/M in Libala South, Off Kasama Road, P. O. Box 30075, Lusaka, Zambia.
James MwansaDirectorate of Research, Statistics and Postgraduate Studies, Lusaka Apex Medical University, P. O. Box 31909, Lusaka, Zambia.
Godfrey BiembaNational Health Research Authority, Office of the Director and Chief Executive Officer, Lot No. 1896/M in Libala South, Off Kasama Road, P. O. Box 30075, Lusaka, Zambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial resistance (AMR) is a major global threat, projected to cause 10 million deaths annually by 2050, mostly in sub-Saharan Africa. Indiscriminate dispensing and policy non-adherence worsen AMR, yet non-prescription antimicrobial use persists. This study examines over-the-counter (OTC) antimicrobial dispensing by pharmacy personnel in Lusaka Province, Zambia. Objective: To describe OTC antimicrobial dispensing by retail pharmacy personnel in Lusaka Province and its implications for AMR. Methods: We conducted a cross-sectional survey using simulated clients at 142 retail pharmacies to assess OTC antimicrobial dispensing practices. Results: Of the 142 retail pharmacies in Lusaka visited by simulation clients seeking antimicrobials without prescriptions, 90.1% complied with the requests. While 28.9% mentioned that a prescription was needed, only 25.4% advised clients to obtain one. Additionally, 83.3% recommended buying antimicrobials instead of visiting a hospital, with in-pharmacy treatment rates of 86.7% for Upper Respiratory Tract Infection symptoms, 90.5% for cough and 91.7% for sore throat. Conclusions: We observed a high level of OTC antimicrobial dispensing among retail pharmacy personnel in Lusaka Province, which may hinder efforts to combat AMR in Zambia. Although the study lacked qualitative data to explore the reasons behind this practice, such research is urgently needed. Nonetheless, our findings highlight the need for the ZMRA to enhance monitoring of retail pharmacies to ensure adherence to international antimicrobial dispensing standards and help reduce AMR.

Identifiers

PMID40583999
PMCPMC12204315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.