Evidence map›Paper›PMID 40583993›Full record

ArticleJAC-antimicrobial resistance2025

S Giuliano, A Piccirilli, J Angelini, F Patriarca, R Fanin, L Martini, T Semenzin, M Fanin, S Lanini, R A Bonomo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

S GiulianoInfectious Diseases Clinic, Azienda Sanitaria Universitaria del Friuli Centrale (ASUFC), Udine, Italy.ORCID https://orcid.org/0000-0003-2475-8732
A PiccirilliDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
J AngeliniDepartment of Medicine (DMED), University of Udine, Udine, Italy.
F PatriarcaDepartment of Medicine (DMED), University of Udine, Udine, Italy.
R FaninDepartment of Medicine (DMED), University of Udine, Udine, Italy.
L MartiniInfectious Diseases Clinic, Azienda Sanitaria Universitaria del Friuli Centrale (ASUFC), Udine, Italy.ORCID https://orcid.org/0009-0007-3160-0171
T SemenzinInfectious Diseases Clinic, Azienda Sanitaria Universitaria del Friuli Centrale (ASUFC), Udine, Italy.
M FaninHaematological Clinic and Transplant Centre, Azienda Sanitaria Universitaria del Friuli Centrale (ASUFC), Udine, Italy.
S LaniniInfectious Diseases Clinic, Azienda Sanitaria Universitaria del Friuli Centrale (ASUFC), Udine, Italy.
R A BonomoMedical Service and Center for Antimicrobial Resistance and Epidemiology, Louis Stokes Cleveland Veterans Affairs Medical Center, University Hospitals Cleveland Medical Center and Departments of Medicine, Pharmacology, Molecular Biology, and Microbiology, Case Western Reserve University, Cleveland, OH, USA.ORCID https://orcid.org/0000-0002-3299-894X
M PerilliDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
C TasciniInfectious Diseases Clinic, Azienda Sanitaria Universitaria del Friuli Centrale (ASUFC), Udine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We report a case of bloodstream infection (BSI) caused by an Results: The patient responded favourably to CZA therapy (2.5 g every 8 h via continuous infusion for 9 days), with rapid microbiological clearance and clinical improvement. TDM confirmed therapeutic plasma concentrations of both ceftazidime (29.57 mg/L) and avibactam (5.52 mg/L). Genomic analysis revealed multiple resistance genes ( Conclusions: This case illustrates the clinical utility of a carbapenem-sparing strategy guided by TDM in a high-risk, ARC patient with an AmpC-producing

Identifiers

PMID40583993
PMCPMC12203789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.