ArticleTherapeutic advances in gastroenterology2025
Tailored therapy guided by genotypic resistance from gastric mucosa samples in the first-line treatment of
Article in Therapeutic advances in gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Treatment of Helicobacter pylori Infection in Korea: An Evidence-Based Analysis of the Upcoming 2025 Guideline.The Korean journal of helicobacter and upper gastrointestinal research · 2026Review
- Comparative effectiveness of genotype-guided and empirical bismuth-containing quadruple therapy forFrontiers in pharmacology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Tailored therapy is crucial for reducing the irrational use of antibiotics and enhancing Objectives: This study aims to clarify the efficacy, safety, patient compliance, and cost-effectiveness of genotypic resistance-guided tailored therapy for first-line Design: A systematic review and meta-analysis following the PRISMA 2020 guidelines. Data sources and methods: The literature was searched in PubMed, Web of Science, and Wanfang databases under the keywords " Results: Of 1524 retrieved articles, 29 (including 4895 patients) met inclusion criteria for single-arm meta-analysis, and 17 (including 6208 patients) were included in the classical meta-analysis by further excluding studies that did not use empirical treatment as control. The single-arm meta-analysis demonstrated satisfactory efficacy of tailored therapy in first-line Conclusion: Tailored therapy guided by genotypic resistance detected from gastric mucosa samples demonstrates satisfactory eradication efficacy in first-line Trial registration: This study was not registered in PROSPERO, and future systematic reviews and meta-analyses will be registered in advance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.