Evidence map›Paper›PMID 40583876›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2025

Correlation Between Lipid Accumulation Product and Metabolic Dysfunction-Associated Steatotic Liver Disease in Chinese Adults with Type 2 Diabetes Mellitus.

Wei Liu, Lingling Xu, Yuan Yu, Liang Qiao, Lijuan Zhang, Xiaoqiu Chu, Haibo Jing, Lin Cao

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei Liu *Department of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, People's Republic of China.
Lingling Xu *Department of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, People's Republic of China.ORCID 0009-0000-8100-8976
Yuan YuDepartment of Gastroenterology, Jiangning Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu, 211100, People's Republic of China.
Liang QiaoDepartment of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, People's Republic of China.
Lijuan ZhangDepartment of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, People's Republic of China.
Xiaoqiu ChuDepartment of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, People's Republic of China.
Haibo JingDepartment of General Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, People's Republic of China.ORCID 0000-0002-1889-8483
Lin CaoDepartment of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, People's Republic of China.ORCID 0000-0001-5245-7457

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the value and feasibility of the lipid accumulation product (LAP) in the prediction of metabolic dysfunction-associated steatotic liver disease (MASLD) in Chinese adults with type 2 diabetes mellitus (T2DM). Methods: In this cross-sectional study, we assessed the value of LAP and other novel indices in the prediction of MASLD in Chinese adults with T2DM in a total of 642 patients. Receiver Operating Characteristic (ROC) curves were plotted to assess the predictive ability of the indices for the occurrence of MASLD in T2DM. Results: The results showed that LAP had a strong predictive ability for the occurrence of MASLD in T2DM in both men and women and was superior to other traditional visceral fat-related indices. In men, the area under curve (AUC) (95% CI) was 0.815 (0.771-0.859) with cut-off value of 36.01, and its sensitivity and specificity were 71.91% and 77.44%, respectively. And in women, the AUC (95% CI) was 0.816 (0.762-0.870) with cut-off value of 24.22, and its sensitivity and specificity were 84.93% and 63.54%, respectively. Conclusion: LAP has a high predictive ability for the occurrence of MASLD in T2DM in both men and women and are superior to other traditional visceral fat-related indices.

Indexed as

diabetes mellituslipid accumulation productmetabolic dysfunction-associated steatotic liver diseasetype 2

Identifiers

PMID40583876
PMCPMC12205747

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.