Evidence map›Paper›PMID 40583737›Full record

ArticleAmerican journal of biological anthropology2025

Trabecular Architecture of the Proximal Tibia in Extant Hominids.

Andrea Lukova, Sebastian Bachmann, Alexander Synek, Dieter H Pahr, Brandon Kilbourne, Christopher J Dunmore, Tracy L Kivell, Matthew M Skinner

Abstract read
In one paragraph

Article in American journal of biological anthropology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Trabecular Architecture of the Proximal Tibia in Extant Hominids.American journal of biological anthropology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea LukovaDepartment of Human Origins, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0009-0001-9843-336X
Sebastian BachmannInstitute of Lightweight Design and Structural Biomechanics, Wien, Austria.
Alexander SynekInstitute of Lightweight Design and Structural Biomechanics, Wien, Austria.
Dieter H PahrInstitute of Lightweight Design and Structural Biomechanics, Wien, Austria.
Brandon KilbourneLeibniz Institute for Research on Evolution and Biodiversity, Berlin, Germany.
Christopher J DunmoreSchool of Biosciences, University of Kent, Canterbury, UK.ORCID 0000-0002-8634-9777
Tracy L KivellDepartment of Human Origins, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0001-5087-0897
Matthew M SkinnerDepartment of Human Origins, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

Funding

H2020 European Research Council 819960
6 · The paper itself

Abstract

objectivesExtant humans and non-human apes are characterized by diverse locomotor and postural behaviors, resulting in different joint loading patterns. These behaviors influence trabecular bone, which responds to mechanical loading and joint posture. While prior studies have examined femoral trabecular structure, this study is the first to assess trabecular architecture in the proximal tibia across extant hominoids to evaluate how differences in joint use and posture are reflected in tibial morphology. MATERIALS AND

methodsWe analyze trabecular structure in the proximal tibiae of Homo sapiens (n = 25), Gorilla (n = 13), Pan troglodytes (n = 15) and Pongo sp. (n = 7). Each tibia was scanned using high-resolution microtomography, and cortical and trabecular bone were isolated from each other. Canonical holistic morphometric analysis was used to quantify trabecular bone volume fraction and degree of anisotropy. Spatial distributions of these variables were compared across taxa using principal component analysis, and group differences were assessed with multivariate analysis of variance and pairwise tests.

resultsResults show that trabecular bone volume and anisotropy reflect habitual knee posture: extended in bipedal Homo, and flexed in non-human apes. In Gorilla, males exhibit more extended knee use than females, while no significant sex differences were observed in Homo or Pan (sex differences in Pongo were not tested due to sample limitations). DISCUSSION: We demonstrate that the trabecular structure of the proximal tibia is consistent with habitual locomotor loading in extant hominids, which provides the comparative context to interpret knee posture, biomechanical loading, and predominant locomotor behaviors in fossil hominids.

Indexed as

Cancellous BoneHominidaeTibiaAnimalsAnthropology, PhysicalFemaleHumansMaleX-Ray Microtomographybipedalismfunctional morphologyGorillahumankneelocomotor behaviorPanPongo

Identifiers

PMID40583737
PMCPMC12207363

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.