Evidence map›Paper›PMID 40583598›Full record

ArticleJournal of sleep research2026

Treatment Preferences in Patients With Insomnia and Medical Comorbidity: Associated Factors and Impact on Treatment-Outcome.

Nynke Rauwerda, Irene Pot, Annemarie Braamse, Annemieke van Straten, Pythia van Nieuwkerk, Myrthe Boss, Marian Rikkert, Hans Knoop

Abstract readEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nynke RauwerdaDepartment of Medical Psychology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.ORCID 0000-0003-4246-4543
Irene PotDepartment of Medical Psychology, Hospital Gelderse Vallei, Ede, the Netherlands.
Annemarie BraamseDepartment of Medical Psychology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Annemieke van StratenDepartment of Clinical Psychology & Amsterdam Public Health Research Institute, VU University, Amsterdam, the Netherlands.
Pythia van NieuwkerkDepartment of Medical Psychology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Myrthe BossDepartment of Neurology, Hospital Gelderse Vallei, Ede, the Netherlands.
Marian RikkertDepartment of Medical Psychology, Hospital Rivierenland, Tiel, the Netherlands.
Hans KnoopDepartment of Medical Psychology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.

Funding

Hospital Gelderse Vallei, Ede, Netherlands
6 · The paper itself

Abstract

Insomnia is common in patients with medical comorbidity. First-line treatment for insomnia is cognitive behavioural therapy for insomnia (CBT-I). However, some patients with medical comorbidities prefer pharmacological treatment. This study aimed to (1) identify factors influencing treatment preference in these patients, and (2) assess how aligning treatment with patient preferences impacts outcomes for CBT-I and low-dose Amitriptyline. This study was part of a non-inferiority randomised controlled trial. The study involved 187 participants who were randomly assigned to either CBT-I or Amitriptyline for 12 weeks and 54 participants who refused to participate in the randomised controlled trial. Treatment preferences were assessed at baseline using the Treatment Perception and Preferences (TPP) questionnaire and insomnia severity was assessed before and after treatment with the Insomnia Severity Index (ISI). Multiple and linear regression analyses (p < 0.001, adj. R

Indexed as

AmitriptylineCognitive Behavioral TherapyPatient PreferenceSleep Initiation and Maintenance DisordersAdultAgedComorbidityFemaleHumansMaleMiddle AgedSeverity of Illness IndexSurveys and QuestionnairesTreatment OutcomeAmitriptylineamitriptylineCBT‐Icognitive behavioural therapy for insomniamedical conditions

Identifiers

PMID40583598
PMCPMC12856101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.