Evidence map›Paper›PMID 40583479›Full record

ArticleBiomarkers in medicine2025

Analyzing the association between MPO levels and glaucoma severity.

Lingling Chen, Jinxia Wang, Yanping Gao, Wenbo Xiu, Zuo Wang, Gao Zhang, An Li, Yang Chen, Bolin Deng, Fang Lu and 2 more

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In one paragraph

Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Lingling ChenDepartment of Immunology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, China.
Jinxia WangClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Yanping GaoCore laboratory, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Wenbo XiuClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Zuo WangClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Gao ZhangClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
An LiClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Yang ChenClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Bolin DengDepartment of Ophthalmology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Fang LuClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Chong HeClinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Lijuan HuDepartment of Immunology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo explore the relationship between plasma myeloperoxidase (MPO) and glaucoma, assessing the clinical utility of MPO in glaucoma.

methodsA cross-sectional study involved 127 glaucoma patients and 106 healthy controls. Plasma MPO markers were quantified using enzyme-linked immunosorbent assay (ELISA), comparing levels between glaucoma patients and healthy controls, and analyzing plasma MPO across different glaucoma severity grades.

resultsIn this study, we observed elevated plasma MPO levels in glaucoma patients (

conclusionElevated plasma MPO levels are independently associated with glaucoma risk, suggesting it might provide insight into disease pathogenesis.

Indexed as

GlaucomaPeroxidaseAgedBiomarkersCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedROC CurveSeverity of Illness IndexBiomarkersMPO protein, humanPeroxidasedisease severityglaucomainflammationoxidative stressPlasma myeloperoxidase

Identifiers

PMID40583479
PMCPMC12258260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.