Evidence map›Paper›PMID 40583475›Full record

Observational studyJournal of human lactation : official journal of International Lactation Consultant Association2025

Relationship Between Birthweight for Gestational Age and Colostrum Macronutrient Composition: A Comparative Analysis in Small, Appropriate, and Large for Gestational Age Infants.

Sema Arayici, Evrim Alyamac Dizdar, Gulsum Kadioglu Simsek, Fatma Nur Sari

Abstract readObservational StudyComparative Study
In one paragraph

Observational study in Journal of human lactation : official journal of International Lactation Consultant Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sema ArayiciDivision of Neonatology, Department of Pediatrics, Akdeniz University School of Medicine, Antalya, Turkiye.ORCID 0000-0002-5389-1834
Evrim Alyamac DizdarDivision of Neonatology, Ankara City Hospital, University of Health Sciences, Ankara, Turkiye.
Gulsum Kadioglu SimsekDivision of Neonatology, Ankara City Hospital, University of Health Sciences, Ankara, Turkiye.
Fatma Nur SariDivision of Neonatology, Ankara City Hospital, University of Health Sciences, Ankara, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman milk and colostrum have been well studied; however, limited data are available on the variations in macronutrient content when compared across different infant weight categories for infants with similar gestational ages. RESEARCH

aimsTo compare the colostrum macronutrient content of participants who delivered term infants classified as small for gestational age, appropriate for gestational age, and large for gestational age.

methodsIn this exploratory cross-sectional observational study (

resultsMedian colostrum protein content was significantly higher in the small for gestational age (4.8 [IQR = 3-6.4] gr/dl) and large for gestational age (4.4 [IQR = 3.5-5.3] g/dl) groups compared to the appropriate for gestational age group (2.8 [IQR = 2.1-3.7] g/dl;

conclusionColostrum macronutrient content varies depending on whether the birthweight is small or large for gestational age. Studies are needed to investigate these potential associations and the clinical consequences of this relationship.

Indexed as

Birth WeightColostrumInfant, Small for Gestational AgeNutrientsAdultCross-Sectional StudiesFemaleGestational AgeHumansInfant, NewbornMaleMilk, HumanPregnancyNutrientsbreastfeedingcolostrumcross-sectional studyhuman milkinfant growthlactationmilk composition

Identifiers

PMID40583475
PMCPMC12238673

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.