Evidence map›Paper›PMID 40583349›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

Coronal plane alignment of the knee classification system does not reliably predict tibiofemoral joint gaps in arthritic knees undergoing total knee arthroplasty.

Ishaan Jagota, Rami M A Al-Dirini, Mark Taylor, Joshua Twiggs, Brad Miles, David Liu

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ishaan Jagota360 Med Care, Sydney, Australia.ORCID https://orcid.org/0000-0002-8240-2120
Rami M A Al-DiriniCollege of Science and Engineering, Flinders University, Adelaide, Australia.ORCID https://orcid.org/0000-0001-6412-6057
Mark TaylorCollege of Science and Engineering, Flinders University, Adelaide, Australia.ORCID https://orcid.org/0000-0001-7842-6472
Joshua Twiggs360 Med Care, Sydney, Australia.ORCID https://orcid.org/0000-0003-0063-0435
Brad Miles360 Med Care, Sydney, Australia.
David LiuThe Gold Coast Centre for Bone and Joint Surgery, Palm Beach, Queensland, Australia.ORCID https://orcid.org/0000-0001-6243-9228

Funding

360 Med Care and Enovis ANZ
6 · The paper itself

Abstract

purposeAchieving optimal mediolateral balance in extension and flexion is critical for improving outcomes in total knee arthroplasty (TKA). Knee classification tools, like coronal plane alignment of the knee (CPAK), do not directly consider the soft tissue profile of the joint. This study evaluated the variation in tibiofemoral gap measurements across CPAK phenotypes and examined the relationships between preoperative tibiofemoral joint gaps and the arithmetic hip-knee-ankle angle (aHKA) and joint line obliquity (JLO), important for TKA planning and execution.

methodsA retrospective analysis of 433 knees from the Joint Dynamics Registry computed tomography (CT) database was performed. Patients received preoperative long-leg CT scans and extension and flexion distracted radiographs. The CT scans were segmented and landmarked to produce three-dimensional bone models and derive anatomical measurements, including aHKA and JLO. The models were registered to the two distracted radiographs, and an osteophyte correction algorithm was applied to calculate the medial and lateral joint gaps in extension and flexion. Composite gap measurements (mean and difference) were also determined. Pearson's correlation and multivariate regression assessed the relationships between joint gaps and aHKA and JLO. ANOVA compared joint gaps across CPAK groups.

resultsSmall but statistically significant differences in joint gap measurements were observed between CPAK groups I and III, and II and III. Weak univariate correlations were observed between aHKA and joint gaps (r ≤ |0.32 |), with fewer statistically significant relationships for JLO (r ≤ |0.15 |). Multivariate regression explained only 10.2% and 1.4% of aHKA and JLO variance, respectively.

conclusionWhile useful for describing coronal alignment, CPAK displayed limited predictive capability for preoperative tibiofemoral joint gaps in TKA patients. Direct assessment of joint gaps remains crucial for surgical planning. Future research should focus on integrating joint gap measurements with bony morphology in preoperative planning workflows to improve TKA personalisation. LEVEL OF EVIDENCE: Level II.

Indexed as

Arthroplasty, Replacement, KneeKnee JointOsteoarthritis, KneeAgedAged, 80 and overFemaleFemurHumansMaleMiddle AgedRange of Motion, ArticularRetrospective StudiesTibiaTibiofemoral JointTomography, X-Ray ComputedCPAKjoint balancejoint gapspreoperative planningtotal knee arthroplasty

Identifiers

PMID40583349
PMCPMC12459326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.