ArticleMicrobiologyOpen2025
Genotypic Analysis of Candida tropicalis Clinical Isolates From Korea via Multilocus Sequence Typing.
Article in MicrobiologyOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Epidemiology, risk factors, and antifungal susceptibility analysis of Candida tropicalis and non-C.tropicalis candidemia.BMC infectious diseases · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Candida tropicalis is a clinically significant non-albicans species that has shown increasing azole resistance globally. Despite its growing clinical importance, genotypic and epidemiological data from East Asia, particularly Korea, remain limited. This study aimed to expand the global understanding of C. tropicalis population structure by genotyping clinical isolates from Korea and identifying novel sequence types. Thirty-four clinical isolates collected from tertiary hospitals across Korea between 2012 and 2019 were analyzed using multilocus sequence typing (MLST) based on six housekeeping genes (ICL1, MDR1, SAPT2, SAPT4, XYR1, and ZWF1). A total of 21 diploid sequence types (DSTs) were identified, including three novel DSTs (1418, 1419, and 1420) not previously recorded in the MLST central database. Notably, DST844 (CTR-19 isolate) exhibited elevated minimum inhibitory concentration (MIC) to fluconazole, suggesting a potential novel resistance phenotype. Phylogenetic and goeBURST analyses revealed 11 distinct clonal complexes (CCs), some of which showed similarity to Chinese and Brazilian lineages, indicating cross-regional evolutionary links. These findings enhance the global MLST data set, provide new insights into the molecular epidemiology of C. tropicalis in Korea, and highlight the need for continued antifungal resistance surveillance, particularly for emerging DSTs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.