Evidence map›Paper›PMID 40583284›Full record

Observational studyInternational wound journal2025

Investigation of Optimal Parameters Setting for Negative Pressure Wound Therapy With Instillation and Dwell Time for Hard-To-Heal Wounds With Necrotic Tissue.

Norihiko Ohura, Masanobu Sakisaka, Daisuke Nakayama, Mikio Kinoshita

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International wound journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Norihiko OhuraDepartment of Plastic Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Masanobu SakisakaDepartment of Plastic Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Daisuke NakayamaDepartment of Plastic Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Mikio KinoshitaDepartment of Plastic Surgery, Kyorin University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Negative Pressure Wound Therapy (NPWT) is a standard treatment for chronic wounds. In 2017, NPWT with instillation and dwell time (NPWTi-d) was approved for insurance coverage in Japan. This study aimed to identify optimal NPWTi-d parameter settings for hard-to-heal wounds with necrotic tissue. We conducted a retrospective observational study of consecutive patients treated with NPWTi-d between August 2017 and February 2019. Parameters analyzed included dressing change frequency (three times per week vs. once per week), therapy duration (2, 3, or 3.5 h), negative pressure levels (50-125 mmHg), dwell time (1-10 min), and instillation volume (mL/cm

Indexed as

NecrosisNegative-Pressure Wound TherapyWound HealingAdultAgedAged, 80 and overFemaleHumansJapanMaleMiddle AgedRetrospective StudiesTime FactorsTreatment Outcomenegative pressure wound therapynegative pressure wound therapy with instillation and dwellingNPWTNPWTi‐dwound healing time

Identifiers

PMID40583284
PMCPMC12206848

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.