Evidence map›Paper›PMID 40583083›Full record

ArticleLasers in medical science2025

Photodynamic antibacterial activity of green-synthesized gold nanoparticles from mangosteen peel extract using blue laser irradiation.

Deny Arifianto, Suryani Dyah Astuti, Baby Mutiara Lusiani, Andi Hamim Zaidan, Winarno Winarno, Ahmad Khalil Yaqubi, Yunus Susilo, Karwan Wasman Qadir, Ardiansyah Syahrom

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Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deny ArifiantoFaculty of Science and Technology, Airlangga University, Surabaya, East Java, 60115, Indonesia.
Suryani Dyah AstutiDepartment of Physics, Faculty of Science and Technology, Airlangga University, Surabaya, 60115, Indonesia. suryanidyah@fst.unair.ac.id.
Baby Mutiara LusianiDepartment of Physics, Faculty of Science and Technology, Airlangga University, Surabaya, 60115, Indonesia.
Andi Hamim ZaidanDepartment of Physics, Faculty of Science and Technology, Airlangga University, Surabaya, 60115, Indonesia.
Winarno WinarnoDepartment of Physics, Faculty of Science and Technology, Airlangga University, Surabaya, 60115, Indonesia.
Ahmad Khalil YaqubiDepartment of Physics, Faculty of Science and Technology, Airlangga University, Surabaya, 60115, Indonesia.
Yunus SusiloFaculty of Engineering, Universitas Dr Soetomo Surabaya, Surabaya, 60118, Indonesia.
Karwan Wasman QadirDepartement of Physics, College of Education, Salahaddin University, Erbyl, Iraq.
Ardiansyah SyahromMedical Devices and Technology Centre, Universiti Teknologi Malaysia, Bahru, 81310, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductiondiseases caused by antibiotic-resistant bacteria pose a growing global health challenge. Photodynamic Therapy (PDT), which uses light-activated photosensitizers to kill bacteria, offers a promising alternative. This study evaluates the antibacterial efficacy of gold nanoparticles synthesized from mangosteen peel extract (AuNPs-GML) combined with blue diode laser irradiation against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), two common pathogens. MATERIALS AND

methodsFour treatments were applied: control (no treatment), AuNPs-GML alone, blue laser irradiation alone (405 nm), and a combination of AuNPs-GML with laser irradiation. Samples were incubated at 37 °C for 24 h before bacterial viability was assessed. Statistical analysis was performed using Two-Way ANOVA and Tukey's post hoc test (p < 0.05).

resultsResults showed that combining AuNPs-GML with blue laser irradiation significantly enhanced bacterial inactivation compared to laser or nanoparticles alone. At 180 seconds irradiation and 2 mM AuNPs-GML concentration, bacterial reduction reached 86.25% for E. coli and 72.84% for S. aureus at an energy density of 3.34 J/cm2.

conclusionThis study demonstrates the potential of AuNPs-GML activated by blue laser PDT as an effective antibacterial treatment against resistant bacteria.

Indexed as

Anti-Bacterial AgentsGarcinia mangostanaGoldLasers, SemiconductorMetal NanoparticlesPhotochemotherapyPlant ExtractsEscherichia coliGreen Chemistry TechnologyPhotosensitizing AgentsStaphylococcus aureusAnti-Bacterial AgentsGoldPhotosensitizing AgentsPlant ExtractsBlue LaserEscherichia coliPhotodynamic TherapyPhotosensitizerStaphylococcus aureus

Identifiers

PMID40583083

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.