Evidence map›Paper›PMID 40583078›Full record

ArticleWorld journal of pediatrics : WJP2025

Prognosis and influencing factors of pulmonary embolism in children: a multicenter study.

Zhi-Lang Lin, Shu-Han Zeng, Feng-Qin Liu, Tian Shen, Zi-Chao Lyu, Le-Jia Zhang, Yue-Lun Zhang, Rui-Ming Liang, Xing Chen, Hui-Juan Xu and 10 more

Erratum issuedAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of pediatrics : WJP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Zhi-Lang LinDepartment of Pediatric Nephrology and Rheumatology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Shu-Han ZengDepartment of Pediatric Nephrology and Rheumatology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Feng-Qin LiuPediatric Respiratory Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China.
Tian ShenDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Zi-Chao LyuDepartment of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuai Fu Yuan, Beijing, 100730, China.
Le-Jia ZhangDepartment of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuai Fu Yuan, Beijing, 100730, China.
Yue-Lun ZhangCentral Research Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Rui-Ming LiangClinical Trials Unit, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Xing ChenPediatric Respiratory Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China.
Hui-Juan XuDepartment of Pediatrics, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, 266003, China.
Gang LiuDepartment of Infectious Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Bing LiuDepartment of Infectious Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Yuan WenDepartment of Pediatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, 100176, China.
Yi ZhangDepartment of Pediatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, 100176, China.
Meng-Ze HuDepartment of Hematology, Children's Hospital Capital Institute of Pediatrics, Beijing, 100020, China.
Rong LiuDepartment of Hematology, Children's Hospital Capital Institute of Pediatrics, Beijing, 100020, China.
Xiao-Chuan WuDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Xiao-Yun JiangDepartment of Pediatric Nephrology and Rheumatology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. jxiaoy@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-4044-2500
Li-Rong SunDepartment of Pediatrics, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, 266003, China. sunlr@vip.sina.com.
Juan XiaoDepartment of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuai Fu Yuan, Beijing, 100730, China. xiaojuan@pumch.cn.

Funding

the CAMS Innovation Fund for Medical Sciences (CIFMS) 2022-I2M-C&T-B-009
6 · The paper itself

Abstract

backgroundThe incidence of pediatric pulmonary embolism is increasing, with varying clinical characteristics, severity, and prognosis. Compared with data from adults, data and knowledge regarding the prognosis of pediatric pulmonary embolism are scarce. This study aims to study the overall prognosis of pediatric pulmonary embolism and explore its influencing factors.

methodsThe study included patients diagnosed with pulmonary embolism aged 1-18 years across eight tertiary referral hospitals from January 1, 2003, to December 31, 2023. Pulmonary embolism was diagnosed on the basis of clinical presentation with imaging evidence. The overall prognosis of children with pulmonary embolism was reported, and its influencing factors were analyzed.

resultsA total of 196 children were enrolled, with a median age of 11.8 (7.9, 15.4) years, 113 males (58%) and 186 Han (95%). The overall mortality rates were 2.2% at 30 days, 3.4% at 90 days, and 5.1% during the entire follow-up period. The pulmonary embolism-related mortality rates were 1.6% (30 days), 2.7% (90 days), and 2.6% (entire follow-up period). Deep vein thrombosis at other sites occurred in 2.7% (30 days), 4.1% (90 days), and 7.6% (entire follow-up period) of the children. Among the 148 children who underwent repeat imaging examinations, 119 (81%) achieved complete remission; 24 (16%) achieved partial remission; and 4 (3%) experienced recurrence or progression during the follow-up period. Multivariable logistic regression analysis revealed that tachypnea, co-infection, and underlying disease of the tumor were independent risk factors for compound adverse events (death, pulmonary embolism progression/recurrence, and at other sites) within 90 days.

conclusionsThe short-term mortality of children with pulmonary embolism was relatively low. Children with pulmonary embolism who had tachypnea, co-infection, or underlying disease of the tumor were at increased risk of compound adverse events within 90 days.

Indexed as

Pulmonary EmbolismAdolescentChildChild, PreschoolChinaFemaleHumansInfantMalePrognosisRetrospective StudiesRisk FactorsChildrenPrognosisPulmonary embolismRisk factors

Identifiers

PMID40583078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.