ReviewInflammation research : official journal of the European Histamine Research Society ... [et al.]2025
Biological attributes of zinc-dependent endopeptidases in endothelial dysfunction associated with sepsis: a narrative review.
Review in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Ratiometric Fluorescent Sensing of MMP-3 via FRET for Postoperative Rehabilitation Assessment and Prognostic Monitoring Following Joint Surgery.Journal of fluorescence · 2026Article
- Investigation of the effects of acrylamide on tendon healing in rats.Acta orthopaedica et traumatologica turcica · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Understanding of the pathophysiology of sepsis allows the development of new therapeutic approaches, beyond supportive care and antimicrobial therapy, to help reduce the high mortality rates in intensive care units. In this context, a large number of experimental and clinical studies in the last 20 years support the key role of the endothelium in sepsis in relation to organ failure. This review aims to provide a comprehensive overview of the role of zinc-dependent endopeptidases and their endogenous inhibitors in endothelial dysfunction associated with sepsis as well as in other pathologies. Finally, we discuss that inhibitors of this family of proteases could represent a promising therapeutic approach against sepsis.
Indexed as
Identifiers
40583077What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.