ArticleThe world journal of men's health2026
Development of a New Diagnostic Tool (LUTS/BPH Score) for Male Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia.
Article in The world journal of men's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Disease Progression and Outcomes in Patients With Benign Prostatic Hyperplasia: Protocol for a Multicenter Retrospective Cohort Study.JMIR research protocols · 2026Article
- Impact of Androgen Deprivation Therapy on Lower Urinary Tract Symptoms in Patients with Prostate Cancer.Medicina (Kaunas, Lithuania) · 2026Article
- Safety and efficacy of thulium laser enucleation of the prostate within two weeks following transperineal biopsy.Lasers in medical science · 2026Article
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Authors and funding
33 authors.
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Abstract
purposeTo develop a new diagnostic tool, the LUTS/BPH score, for male lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH), which integrates the International Prostate Symptom Score (IPSS), prostate size, and urinary flow rate. MATERIALS AND
methodsFrom an initial pool of 75,199 subjects, 12,891 patients met the inclusion criteria. For the statistical analysis used to develop the new LUTS/BPH score, data were refined through outlier removal, normalization, and the collection of relevant variables. Weights for the relevant variables were determined using principal component analysis (PCA).
resultsThe new LUTS/BPH score was developed using the three variables: IPSS, prostate size, and maximum urinary flow rate (Qmax). The LUTS/BPH score was calculated by normalizing these variables and applying PCA to determine the weights, resulting in weights of 0.62 for IPSS, -0.64 for Qmax, and 0.46 for prostate size (PCA score=0.62×IPSS -0.64×Qmax+0.46×prostate size). To simplify the LUTS/BPH score calculation in practice, weights were adjusted using IPSS as the reference variable (weight set to 1) and rounded to the first decimal place. The final LUTS/BPH score formula is "LUTS/BPH score=IPSS-Qmax+0.7×prostate size". Based on this distribution, the LUTS/BPH score can classify symptom severity into three categories: (1) Mild symptoms <2, (2) Moderate symptoms: 2-42, and (3) Severe symptoms ≥43.
conclusionsThe newly developed LUTS/BPH score is an objective and quantifiable diagnostic tool for male LUTS due to BPH, supplementing the currently used IPSS with additional key diagnostic indicators such as prostate size and urinary flow rate.
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