ArticleThe world journal of men's health2026
Impact of Varicocele on Pregnancy and Live Birth Outcomes in Men with Clinical Varicocele: Systematic Review of Controlled Studies.
Article in The world journal of men's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Hydrocele is a benign pathology, an appearance disorder: no, this may be a common misconception.Frontiers in urology · 2026Article
- Integrating bibliometrics and real-world data to map varicocele research and predict surgical outcomes.Frontiers in endocrinology · 2026Article
- Advances in immune-inflammatory interactions within the testicular-penile microenvironment of varicocele patients: molecular mechanisms underlying erectile dysfunction and spermatogenic impairment.Frontiers in endocrinology · 2026Review
Corrections and comments
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Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the impact of varicocele on pregnancy and live birth outcomes in men with clinical varicocele in controlled studies. MATERIALS AND
methodsA comprehensive literature search was conducted across the PubMed and Scopus databases using Boolean operators, covering all available records from each database's inception through June 30, 2024. The inclusion criteria focused on controlled studies that compared pregnancy-related outcomes-including pregnancy, miscarriage, and live birth rates-between men with clinical varicocele and those without. These studies included participants attempting conception either spontaneously or through assisted reproductive techniques.
resultsOut of 3,532 articles screened, only two controlled studies met the inclusion criteria. The findings revealed no significant differences between men with and without varicocele in terms of time to achieve pregnancy (5.3
conclusionsThe relationship between varicocele and conception remains contentious, primarily due to the limited number of controlled studies available for analysis. Despite an extensive systematic search for controlled studies comparing pregnancy-related outcomes in men with and without clinical varicocele, only two studies met the inclusion criteria. These studies showed no significant differences in time to achieve pregnancy or previous conception rates between the two groups. However, men with varicocele exhibited a slightly lower, statistically significant, live birth rate compared to men without varicocele. This highlights the need for further research on this topic to provide evidence-based guidance on the impact of varicocele on fertility outcomes.
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