Evidence map›Paper›PMID 40582767›Full record

ReviewChemphyschem : a European journal of chemical physics and physical chemistry2025

Broad-Spectrum Diffusion Coefficient Measurements via Surface Plasmon Resonance: From Thermodynamics to Protein Conformational Disorders.

Giuseppe Stefano Basile, Damiano Calcagno, Nunzio Tuccitto, Diego Sbardella, Giuseppe Grasso

Abstract readReview
In one paragraph

Review in Chemphyschem : a European journal of chemical physics and physical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Enantiopurity-Dependent Peptide Coacervates and Asymmetric Organocatalysis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giuseppe Stefano BasileDepartment of Chemical Sciences, University of Catania, Viale Andrea Doria 6, 95125, Catania, Italy.ORCID 0009-0003-1258-8702
Damiano CalcagnoIRCCS-Fondazione Bietti, Via Livenza 3, 00198, Rome, Italy.ORCID 0000-0002-6105-5983
Nunzio TuccittoDepartment of Chemical Sciences, University of Catania, Viale Andrea Doria 6, 95125, Catania, Italy.ORCID 0000-0003-4129-0406
Diego SbardellaIRCCS-Fondazione Bietti, Via Livenza 3, 00198, Rome, Italy.ORCID 0000-0002-9924-7761
Giuseppe GrassoDepartment of Chemical Sciences, University of Catania, Viale Andrea Doria 6, 95125, Catania, Italy.ORCID 0000-0002-7179-4835

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Information regarding the dimension and the shape of molecules in solution represents a holy grail for chemists. Recently, newly designed surface plasmon resonance (SPR) methods to precisely measure the diffusion coefficients (D) (D-SPR) have been developed and applied successfully to a variety of molecules, ranging from diverse long-chain alcohols to protein conformers and oligomers involved in conformational disorders, mostly represented by neurodegenerative processes of nervous tissues of the brain and retina. The dependence of D on the molecular size, shape, and oligomerization state of different molecules has been widely investigated, opening up new avenues and tools for chemical, biochemical, and clinical research. Herein, the historical basis and the development of the newly proposed D-SPR method are briefly described to obtain meaningful information about molecular features that are otherwise hard to characterize using more common and traditional bioanalytical approaches.

Indexed as

ProteinsSurface Plasmon ResonanceThermodynamicsDiffusionHumansProtein ConformationProteinsaggregationconformational disorderscontinuum mechanicsdiffusionsurface plasmon resonanceTaylor analysisthermodynamics

Identifiers

PMID40582767
PMCPMC12388167

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.