Evidence map›Paper›PMID 40582731›Full record

ReviewCardiology clinics2025

Sex Differences in Cardiovascular Diseases and Vascular Function in Chronic Kidney Disease.

Ester Oh, Kristen Nowak, Silvi Shah

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cardiology clinics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ester OhDivision of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Anschutz Medical Campus, 12700 E 19th Avenue, Aurora, CO 80045, USA.
Kristen NowakDivision of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Anschutz Medical Campus, 12700 E 19th Avenue, Aurora, CO 80045, USA.
Silvi ShahDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: shah2sv@ucmail.uc.edu.

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DANIEL Holland BESSESEN · 1995 to 2026
$32.6M
Sex Disparities in Cardiovascular Disease and Optimal Coronary Revascularization in Dialysis PatientsK23HL151816 · NHLBI · UNIVERSITY OF CINCINNATI · PI SHAH, SILVI · 2021 to 2025
$1.0M
NHLBI NIH HHS K23 HL151816NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney disease (CKD). We summarize the current knowledge of sex differences and associated vascular dysfunction in patients with CKD. We discuss mechanisms that may partially explain the sex differences in cardiovascular risk in CKD, which include sex differences in CKD progression that may uniquely impact the hypothalamic-pituitary-gonadal axis and gonadal hormone production. We also highlight the gaps and challenges in research on sex differences in CVD risk and women's vascular health in CKD, as well as specific future approaches to further research on this topic.

Indexed as

Cardiovascular DiseasesRenal Insufficiency, ChronicFemaleGlobal HealthHumansMaleRisk FactorsSex FactorsCardiovascular diseaseChronic kidney diseaseDialysisSexVascular function

Identifiers

PMID40582731
PMCPMC12209600

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.